From meta (change) and kineō (to move). To move from one place, to shift, to be displaced. Paul uses it of being moved away from the hope of the gospel.
Paul urges the Colossians to continue in the faith, 'not moved away from the hope held out in the gospel' (Colossians 1:23). In a world of shifting opinions and cultural pressure, believers must remain anchored to the unchanging gospel. The word implies that external forces actively try to dislodge believers from their hope — perseverance requires deliberate resistance.