To do, to make, to create, to produce, to perform. Poieō is the general verb for action and making — appearing over 570 times in the NT. It covers God's creative acts, human deeds, and the performance of religious duties. It gives us 'poet' (a maker).
God is the ultimate poiētēs (maker): 'He made the world and everything in it' (Acts 17:24). Jesus said, 'My Father is always working, and I too am working' (John 5:17). Believers are 'God's handiwork [poiēma], created in Christ Jesus to do good works' (Ephesians 2:10). The Christian call is not passive contemplation but active doing — 'Be doers of the word, and not hearers only' (James 1:22).