Antiocheia refers to two cities named Antioch in the New Testament: (1) Antioch in Syria (modern Turkey), the major Gentile church center and the base for Paul's missionary journeys; and (2) Antioch in Pisidia, also visited by Paul. Syrian Antioch was where disciples were first called Christians (Acts 11:26).
Syrian Antioch holds enormous theological significance — it was the first major Gentile church, the launching pad for world missions, and the place where the name "Christian" was first used. The church at Antioch represents the breakthrough of the gospel beyond Jewish boundaries and models the sending church. Every missionary enterprise since traces its spiritual DNA to Antioch.