The Greek adjective apoblētos (from apoballō, 'to throw away') means 'to be thrown away' or 'to be rejected.' In 1 Timothy 4:4, Paul uses it in the negative — 'nothing is to be rejected' — arguing against ascetic food restrictions.
Paul's use of apoblētos (negated: oudén apoblēton) in 1 Timothy 4:4 is a decisive anti-Gnostic and anti-ascetic statement: 'For everything God created is good, and nothing is to be rejected if it is received with thanksgiving.' God's creation is not spiritually contaminated — the Gnostic error was to treat the physical world as a second-class realm to be rejected. Against this, Paul grounds Christian freedom in thankful reception: what God made, received with gratitude and prayer, becomes sanctified for use. The corrective to apoblētos anxiety about creation is not stricter rules but deeper thanksgiving.