A verb meaning 'to sail away,' 'to depart by sea,' or 'to set sail from a port.' Used in Acts for Paul's sea voyages across the Mediterranean.
Apopleo (G636) appears in Acts 13:4, 14:26, 20:15, and 27:1. In Acts 13:4 Paul and Barnabas 'sailed to Cyprus' from Seleucia. In Acts 27:1 Paul's final sea voyage toward Rome begins. The word captures the decisive departure -- casting off, setting sail, leaving a familiar port for unknown waters. Theologically, Paul's sea voyages represent the gospel's expansion across the Mediterranean world -- the sea that Rome dominated became the highway for Kingdom proclamation. Acts is structured around these departures, each one carrying the gospel further toward 'the ends of the earth' (Acts 1:8).