The Greek verb apochorizo means to separate, to part from, or to be torn apart. It combines apo- (away) and chorizo (to separate/divide). In the New Testament, it appears in two contexts: the 'sharp disagreement' that separated Paul and Barnabas, and the cosmic separation described in Revelation.
Apochorizo appears in Acts 15:39 to describe the painful split between Paul and Barnabas over John Mark: 'They had such a sharp disagreement that they parted [apochoristhenai] company.' This is one of the New Testament's most honest moments — two great missionaries, both right in their ways, unable to agree and going separate directions. Yet God redeemed even this separation: Paul and Silas went one direction, Barnabas and Mark another — two missions instead of one. In Revelation 6:14, the sky 'receded like a scroll, rolling up' (apechoristhe) at the breaking of the sixth seal — cosmic separation at the end of the age.