An impersonal verb meaning 'it is possible' or 'it can be.' Used only once in the NT, in Jesus' teaching about the impossibility of a prophet perishing outside Jerusalem — making the 'possible' a theological category.
Jesus uses endechetai in a sharply ironic statement: 'It cannot be that a prophet should perish outside Jerusalem' (Luke 13:33). The irony is devastating — Jerusalem, the city of God's presence, has become the city that kills God's messengers. What should be impossible (the holy city destroying prophets) has become inevitable. This word captures the tragedy of religious institutions that oppose the very God they claim to serve.