Exoudenoo (variant: exoutheneo) means to treat as nothing (ouden = nothing). In Mark 9:12 it is used of the Son of Man being 'treated with contempt.' In Luke 23:11 Herod and his soldiers 'treated him with contempt' and mocked him. The word describes the complete dismissal of someone's worth or significance — treating a person as if they were literally nothing.
The exoudenoo of Jesus by Herod is the fulfillment of Isaiah 53:3: 'despised and rejected by men; a man of sorrows.' The one through whom all things were made is treated as nothing. This is the paradox of the cross: the One of infinite worth receives the treatment of one who is worthless. And He receives it voluntarily, in our place, because He knew our worth even when we could not see His. The contempt shown to the King becomes the currency of our dignity. He was treated as nothing so we might become sons and daughters of God.