An Alexandreus is a native or inhabitant of Alexandria, Egypt — the great cosmopolitan city founded by Alexander the Great, and a major center of Jewish learning and diaspora life.
Alexandrians appear in Acts 6:9 among those who disputed with Stephen, and Apollos (Acts 18:24) was himself an Alexandrian — eloquent, learned, thoroughly grounded in Scripture. Alexandria was home to the Septuagint translation, Philo's Jewish philosophy, and later the great Christian catechetical school. God planted key figures for the gospel's advance in this city. The Alexandrian Jewish community, despite its sophistication, often resisted the gospel, while others like Apollos became powerful instruments of it.