The Greek verb katargeo means to abolish, to render ineffective, to nullify, or to bring to nothing. It combines kata- (down, against) with argeo (to be idle), creating the image of making something completely inoperative.
Katargeo is one of Paul's most theologically loaded words. He uses it to describe what Christ has done to death (2 Timothy 1:10), the power of sin (Romans 6:6), the law's condemnation (Romans 7:2), and even, ultimately, every rule and authority (1 Corinthians 15:24). What seemed permanent is rendered powerless by the gospel.
Theologically, katargeo announces the scope of Christ's victory: not just forgiveness but the complete nullification of everything that stood against life with God — sin, death, condemnation, and the powers of darkness.