Anoia appears twice in the New Testament. In 2 Timothy 3:9, Paul says that those who oppose the truth will not advance because "their folly (anoia) will be plain to all, as was that of those two men." In Luke 6:11, the Pharisees were "filled with anoia" after Jesus healed the man with the withered hand on the Sabbath — their rage was itself the sign of their spiritual blindness. The word thus connects intellectual folly with moral fury: those who reject God's wisdom often become enraged at those who walk in it.
Anoia (from a-privative + nous, mind) literally means "mindlessness" — the absence of rational thought or spiritual understanding. It encompasses both foolish thinking and the rage that accompanies it, describing behavior that has departed from wisdom.